HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: RBM39 (Q14498)
RNA-binding protein 39 (CAPER alpha) (CAPERalpha) (Hepatocellular carcinoma protein 1) (RNA-binding motif protein 39) (RNA-binding region-containing protein 2) (Splicing factor HCC1)
Gene: RBM39

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	28302793, 35271311, 17643375
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 530
+	Hs
		201670 MSI1H_HUMAN (2-340): 5.33e-59: 196: 27.87		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		1054503 DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		1054357 RA1L2_HUMAN (1-302): 4.03e-58: 193: 83.44		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		162048 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		609861 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		852057 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		RBM39_HUMAN (1-530): 2.78e-101: 316: 100.00
+	Hs
		453687 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PUF60_HUMAN (141-513): 7.12e-66: 225: 19.41
+	Hs
		453107 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08
+	Hs
		453331 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PABP4_HUMAN (41-422): 3.94e-60: 211: 17.22
+	Hs
		161948 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08
+	Hs
		516358 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08
+	Hs
		162035 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		PABP4_HUMAN (41-422): 3.94e-60: 211: 17.22
+	Hs
		516424 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		PABP1_HUMAN (41-426): 4.09e-61: 214: 19.08
+	Hs
		453533 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		DAZP1_HUMAN (243-329): 7.18e-19: 90.6: 29.89
+	Hs
		161942 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93
+	Hs
		201699 MSI1H_HUMAN (2-340): 5.33e-59: 196: 27.87		MSI2H_HUMAN (149-309): 3.89e-15: 78.6: 28.57
+	Hs
		162063 RA1L2_HUMAN (1-302): 4.03e-58: 193: 83.44		HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93
+	Hs
		609862 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		ELAV3_HUMAN (434-530): 7.68e-17: 84.2: 12.87
+	Hs
		609833 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		ELAV2_HUMAN (434-530): 7.45e-16: 81.1: 10.89
+	Hs
		161962 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		HNRDL_HUMAN (144-309): 3.62e-15: 79.7: 31.93