HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28977666
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 1912
+	Hs
		162050 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		609866 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		852058 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1059824 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1048064 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1031332 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		453315 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		162028 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		609829 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		852032 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018661 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018471 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018458 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		453629 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Hs
		610059 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Hs
		852179 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Hs
		1020333 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Hs
		1048238 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		CHD8_HUMAN (489-1678): 0: 752: 28.31