HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: RA1L2 (Q32P51)
Heterogeneous nuclear ribonucleoprotein A1-like 2 (hnRNP A1-like 2) (hnRNP core protein A1-like 2)
Gene: HNRNPA1L2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.922

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 34349018, 35235311
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HnRNPA1~HnRNPA1, RRM_1~RRM_1
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003730 - mRNA 3'-UTR binding
GO:0005737 - cytoplasm
GO:0051028 - mRNA transport
GO:0071013 - catalytic step 2 spliceosome
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 372
Hs

1 320
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024