HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	1.00	0.906

Property	Details
Experiments	25324306, 34079125, 17643375, 29845934, 18483487
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 582
+	Hs
		1104152 RA1L2_HUMAN (1-302): 4.03e-58: 193: 83.44		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		162065 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		609895 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		852076 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		403061 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		453331 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		453107 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		161934 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		162035 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		161948 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		516358 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		516424 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		453526 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Hs
		453427 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		453381 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		1077450 DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		162075 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		162059 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		609883 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		852068 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50