HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: NBEL1 (Q6ZS30)
Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein)
Gene: NBEAL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 2694
+	Hs
		852087 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		NBEL2_HUMAN (1-2694): 0: 2268: 44.73
+	Hs
		1169430 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		NBEL2_HUMAN (1-2694): 0: 2268: 44.73
+	Hs
		1020279 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		NBEL2_HUMAN (1-2694): 0: 2268: 44.73
+	Hs
		1048114 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		NBEL2_HUMAN (1-2694): 0: 2268: 44.73
+	Hs
		1031369 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		NBEL2_HUMAN (1-2694): 0: 2268: 44.73
+	Hs
		453251 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		WDR5_HUMAN (2474-2692): 6.07e-64: 223: 16.44
+	Hs
		162000 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		WDR5_HUMAN (2474-2692): 6.07e-64: 223: 16.44
+	Hs
		609790 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		WDR5_HUMAN (2474-2692): 6.07e-64: 223: 16.44
+	Hs
		852006 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		WDR5_HUMAN (2474-2692): 6.07e-64: 223: 16.44
+	Hs
		903463 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		WDR5_HUMAN (2474-2692): 6.07e-64: 223: 16.44
+	Hs
		903216 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		WDR5_HUMAN (2474-2692): 6.07e-64: 223: 16.44
+	Hs
		903196 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		WDR5_HUMAN (2474-2692): 6.07e-64: 223: 16.44
+	Hs
		453269 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		RACK1_HUMAN (2353-2652): 1.1e-20: 97.6: 17.31
+	Dm
		186203 Q8IMS8_DROME (98-189): 7.59e-24: 104: 30.44		GBLP_DROME (2353-2652): 7.79e-21: 98: 17.89
+	Dm
		186223 Q9VBQ1_DROME (98-189): 1.58e-23: 104: 30.44		GBLP_DROME (2353-2652): 7.79e-21: 98: 17.89
+	Hs
		929450 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		RACK1_HUMAN (2353-2652): 1.1e-20: 97.6: 17.31
+	Hs
		929439 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		RACK1_HUMAN (2353-2652): 1.1e-20: 97.6: 17.31