HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: MEPCE (Q7L2J0)
7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-) (Bicoid-interacting protein 3 homolog) (Bin3 homolog)
Gene: MEPCE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.730

Property	Details
Experiments	26186194, 28514442, 29845934, 33961781, 17643375, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:1990904 - ribonucleoprotein complex
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 689
+	Hs
		201685 MSI1H_HUMAN (2-340): 5.33e-59: 196: 27.87		MEPCE_HUMAN (1-689): 0: 1200: 100.00
+	Hs
		1104157 RA1L2_HUMAN (1-302): 4.03e-58: 193: 83.44		MEPCE_HUMAN (1-689): 0: 1200: 100.00
+	Hs
		162080 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		MEPCE_HUMAN (1-689): 0: 1200: 100.00
+	Hs
		609929 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		MEPCE_HUMAN (1-689): 0: 1200: 100.00
+	Hs
		852090 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		MEPCE_HUMAN (1-689): 0: 1200: 100.00
+	Hs
		1184333 PABP3_HUMAN (6-193): 6.86e-35: 137: 17.90		MEPCE_HUMAN (1-689): 0: 1200: 100.00
+	Hs
		1184287 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		MEPCE_HUMAN (1-689): 0: 1200: 100.00
+	Hs
		1048118 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		MEPCE_HUMAN (1-689): 0: 1200: 100.00
+	Hs
		1184260 MSI2H_HUMAN (2-91): 6.69e-16: 79.8: 35.56		MEPCE_HUMAN (1-689): 0: 1200: 100.00
+	Hs
		1031372 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		MEPCE_HUMAN (1-689): 0: 1200: 100.00