HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: CAND1 (Q86VP6)
Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (TBP-interacting protein of 120 kDa A) (TBP-interacting protein 120A) (p120 CAND1)
Gene: CAND1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	HEAT_EZ~HnRNPA1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 1230
+	Hs
		1202045 DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		162088 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		609940 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		852099 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1202069 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1020285 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1048130 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		1031380 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		680463 TIA1_HUMAN (99-193): 5.41e-09: 59.4: 17.71		CAND1_HUMAN (1-1230): 0: 922: 100.00
+	Hs
		155517 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		TNPO2_HUMAN (432-1148): 1.53e-15: 84.2: 12.59
+	Hs
		453517 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		TNPO1_HUMAN (826-1148): 1.51e-09: 64.6: 12.21
+	Dm
		1095699 Q24024_DROME (11-185): 9.7e-38: 142: 38.83		Q9VN44_DROME (175-1181): 1.96e-27: 123: 11.69
+	Hs
		609984 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		TNPO1_HUMAN (826-1148): 1.51e-09: 64.6: 12.21
+	Hs
		852123 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		TNPO1_HUMAN (826-1148): 1.51e-09: 64.6: 12.21
+	Sc
		376762 PABP_YEAST (4-189): 6.12e-39: 147: 24.47		IMB2_YEAST (445-964): 4.58e-11: 69.5: 14.81
+	Dm
		432499 ROA1_DROME (89-192): 4.67e-19: 89.4: 23.08		Q9VN44_DROME (175-1181): 1.96e-27: 123: 11.69
+	Hs
		787481 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		MTOR_HUMAN (11-798): 1.42e-22: 107: 11.87
+	Hs
		1048166 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		TNPO1_HUMAN (826-1148): 1.51e-09: 64.6: 12.21