HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: RBM45 (Q8IUH3)
RNA-binding protein 45 (Developmentally-regulated RNA-binding protein 1) (RB-1) (RNA-binding motif protein 45)
Gene: RBM45

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	1.00	0.715

Property	Details
Experiments	26979993
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 476
+	Hs
		609862 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		ELAV3_HUMAN (7-328): 1.72e-82: 261: 22.84
+	Hs
		162089 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		RBM45_HUMAN (1-476): 1.33e-78: 254: 98.53
+	Hs
		453331 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PABP4_HUMAN (5-411): 7.51e-60: 209: 14.73
+	Hs
		162035 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		PABP4_HUMAN (5-411): 7.51e-60: 209: 14.73
+	Hs
		453511 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		CELF1_HUMAN (126-204): 1.68e-14: 77.5: 23.75
+	Hs
		453107 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PABP1_HUMAN (382-470): 6.62e-13: 72.7: 11.58
+	Hs
		201697 MSI1H_HUMAN (2-340): 5.33e-59: 196: 27.87		CELF1_HUMAN (126-204): 1.68e-14: 77.5: 23.75
+	Hs
		201689 MSI1H_HUMAN (2-340): 5.33e-59: 196: 27.87		CELF5_HUMAN (249-327): 7.27e-14: 75.6: 21.95
+	Hs
		1272074 DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87		CELF1_HUMAN (126-204): 1.68e-14: 77.5: 23.75
+	Hs
		453687 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PUF60_HUMAN (38-180): 7.95e-12: 69.3: 28.28
+	Hs
		453381 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		ELAV1_HUMAN (5-108): 8.6e-12: 68.2: 24.04
+	Hs
		162101 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		CELF1_HUMAN (126-204): 1.68e-14: 77.5: 23.75
+	Hs
		609833 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		ELAV2_HUMAN (353-463): 1.89e-15: 79.4: 20.51
+	Hs
		311334 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		CELF2_HUMAN (255-331): 1.71e-10: 65: 20.25
+	Hs
		453526 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PABP5_HUMAN (396-470): 1.29e-09: 61.9: 16.05
+	Hs
		161948 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		PABP1_HUMAN (382-470): 6.62e-13: 72.7: 11.58
+	Hs
		1077450 DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87		ELAV1_HUMAN (5-108): 8.6e-12: 68.2: 24.04
+	Hs
		516358 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		PABP1_HUMAN (382-470): 6.62e-13: 72.7: 11.58
+	Hs
		162059 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		ELAV1_HUMAN (5-108): 8.6e-12: 68.2: 24.04
+	Hs
		609883 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		ELAV1_HUMAN (5-108): 8.6e-12: 68.2: 24.04