HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	NOPS~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 523
+	Hs
		162097 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		453107 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		453373 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		161948 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		516358 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		162056 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		609879 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		453147 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		609715 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		453526 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PABP5_HUMAN (86-416): 1.38e-52: 184: 16.90
+	Hs
		453331 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		PABP4_HUMAN (3-149): 2.52e-27: 118: 18.83
+	Hs
		162035 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		PABP4_HUMAN (3-149): 2.52e-27: 118: 18.83
+	Hs
		453469 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		RAVR1_HUMAN (84-234): 5.69e-14: 76.4: 23.35
+	Hs
		453381 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		1077450 DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		162059 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		609833 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		ELAV2_HUMAN (84-156): 1.29e-13: 74.1: 31.65
+	Hs
		609883 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		609862 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		ELAV3_HUMAN (84-151): 6.6e-13: 72.2: 32.43
+	Hs
		201707 MSI1H_HUMAN (2-340): 5.33e-59: 196: 27.87		RBM4B_HUMAN (83-190): 4.07e-09: 60.5: 33.04