HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: ACE2 (Q9BYF1)
Angiotensin-converting enzyme 2 (EC 3.4.17.23) (Angiotensin-converting enzyme homolog) (ACEH) (Angiotensin-converting enzyme-related carboxypeptidase) (ACE-related carboxypeptidase) (EC 3.4.17.-) (Metalloprotease MPROT15) [Cleaved into: Processed angiotensin-converting enzyme 2]
Gene: ACE2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	36057605, 36584595, 38245532
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 805
+	Hs
		1104176 RA1L2_HUMAN (1-302): 4.03e-58: 193: 83.44		ACE2_HUMAN (12-805): 0: 1184: 100.00
+	Hs
		610032 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		ACE2_HUMAN (12-805): 0: 1184: 100.00
+	Hs
		852157 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		ACE2_HUMAN (12-805): 0: 1184: 100.00
+	Hs
		1048215 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		ACE2_HUMAN (12-805): 0: 1184: 100.00
+	Hs
		1031448 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		ACE2_HUMAN (12-805): 0: 1184: 100.00