HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: WWP1 (Q9H0M0)
NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 2.3.2.26) (Atrophin-1-interacting protein 5) (AIP5) (HECT-type E3 ubiquitin transferase WWP1) (TGIF-interacting ubiquitin ligase 1) (Tiul1) (WW domain-containing protein 1)
Gene: WWP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35264565
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 922
+	Hs
		1290129 DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87		ITCH_HUMAN (1-922): 0: 884: 57.14
+	Hs
		125107 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		125640 DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		125156 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		125264 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		125447 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		453208 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		NEDD4_HUMAN (84-919): 0: 723: 33.52
+	Hs
		125430 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		609749 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		NEDD4_HUMAN (84-919): 0: 723: 33.52
+	Hs
		609933 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		HUWE1_HUMAN (130-921): 1.4e-172: 559: 24.48
+	Sc
		376913 PABP_YEAST (4-189): 6.12e-39: 147: 24.47		TOM1_YEAST (439-921): 2.08e-156: 512: 31.81
+	Hs
		453626 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		SMUF1_HUMAN (6-451): 5.28e-38: 154: 15.82
+	Hs
		610058 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		SMUF1_HUMAN (6-451): 5.28e-38: 154: 15.82
+	Hs
		852178 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		SMUF1_HUMAN (6-451): 5.28e-38: 154: 15.82
+	Hs
		1306025 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		SMUF1_HUMAN (6-451): 5.28e-38: 154: 15.82
+	Hs
		1048237 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		SMUF1_HUMAN (6-451): 5.28e-38: 154: 15.82
+	Hs
		1048262 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		HECW2_HUMAN (141-582): 1.9e-12: 73.8: 16.11