HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	25616961
Identification Methods	two hybrid, pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 624
+	Hs
		610095 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		852196 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		453702 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		1031489 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		680496 TIA1_HUMAN (99-193): 5.41e-09: 59.4: 17.71		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		609801 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		453265 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		609800 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		803528 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23