HitPredict

Interactor 1: COX6C (P09669)
Cytochrome c oxidase subunit 6C (Cytochrome c oxidase polypeptide VIc)
Gene: COX6C

Interactor 2: COX41 (P13073)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1)
Gene: COX4I1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.886

The method score is based on:

Property Details
Experiments 29568061, 34079125, 33961781, 37071682
Identification Methods proximity labelling technology, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains COX4~COX6C
Common GO terms GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005751 - mitochondrial respiratory chain complex IV
GO:0006091 - generation of precursor metabolites and energy
GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen
and 2 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 75
Hs

1 169
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024