Interactor 1: GIP (P09681)
Gastric inhibitory polypeptide (GIP) (Glucose-dependent insulinotropic polypeptide) (Incretin hormone)
Gene: GIP
Interactor 2: GIPR (P48546)
Gastric inhibitory polypeptide receptor (GIP-R) (Glucose-dependent insulinotropic polypeptide receptor)
Gene: GIPR
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.53 | 0.90 | 0.696 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17715056 |
| Identification Methods | x-ray crystallography, circular dichroism, isothermal titration calorimetry |
| Interaction Type | association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 7tm_2~Hormone_2, HRM~Hormone_2 |
| Common GO terms | GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0009749 - response to glucose GO:0031018 - endocrine pancreas development GO:0032024 - positive regulation of insulin secretion GO:0038192 - gastric inhibitory peptide signaling pathway and 3 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
