HitPredict

Interactor 1: TBA1 (P09733)
Tubulin alpha-1 chain (EC 3.6.5.-)
Gene: TUB1

Interactor 2: TBCB (P53904)
Tubulin-specific chaperone B (Alpha-tubulin formation protein 1) (Tubulin-folding cofactor B)
Gene: ALF1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	9885248, 37968396
Identification Methods	coimmunoprecipitation, two hybrid, affinity chromatography technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005874 - microtubule
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 447 Sc			1 254
+	Sc
		454647 TBA3_YEAST (1-444): 0: 831: 91.22		TBCB_YEAST (1-254): 1.72e-84: 254: 100.00
+	Hs
		933578 TBA4A_HUMAN (1-446): 0: 699: 74.44		TBCB_HUMAN (2-244): 6.1e-73: 224: 28.11
+	Hs
		933320 TBA1B_HUMAN (1-440): 0: 697: 75.23		TBCB_HUMAN (2-244): 6.1e-73: 224: 28.11
+	Hs
		1175122 TBA1A_HUMAN (1-440): 0: 696: 75.46		TBCB_HUMAN (2-244): 6.1e-73: 224: 28.11
+	Sp
		387965 TBA2_SCHPO (1-445): 0: 711: 75.72		ALP11_SCHPO (2-238): 2.91e-63: 199: 26.67
+	Hs
		1175224 TBA1A_HUMAN (1-440): 0: 696: 75.46		CLIP2_HUMAN (26-238): 1.79e-61: 210: 16.14
+	Hs
		675155 TBA4A_HUMAN (1-446): 0: 699: 74.44		CLIP1_HUMAN (129-240): 9.68e-23: 98.8: 22.32
+	Hs
		675189 TBA1A_HUMAN (1-440): 0: 696: 75.46		CLIP1_HUMAN (129-240): 9.68e-23: 98.8: 22.32
+	Hs
		428228 TBB5_HUMAN (1-440): 0: 677: 41.36		TBCE_HUMAN (159-251): 2.21e-25: 106: 29.59
+	Hs
		675240 TBA8_HUMAN (1-441): 0: 679: 73.02		CLIP1_HUMAN (129-240): 9.68e-23: 98.8: 22.32
+	Hs
		428038 TBB5_HUMAN (1-440): 0: 677: 41.36		CLIP1_HUMAN (129-240): 9.68e-23: 98.8: 22.32
+	Sc
		454141 TBA1_YEAST (1-447): 0: 676: 100.00		BIK1_YEAST (174-229): 3.26e-15: 76.5: 33.93