HitPredict

Interactor 1: FGR (P09769)
Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)
Gene: FGR

Interactor 2: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24728074
Identification Methods	pull down, fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005102 - signaling receptor binding GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 529 Hs			1 920
+	Hs
		487088 SRC_HUMAN (1-527): 0: 602: 65.74		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		433225 YES_HUMAN (1-527): 0: 596: 67.83		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		442764 HCK_HUMAN (1-524): 0: 568: 56.30		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		411564 LCK_HUMAN (1-526): 0: 559: 51.90		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		433537 LYN_HUMAN (1-524): 0: 553: 53.91		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		487245 BLK_HUMAN (1-524): 0: 532: 54.10		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		337320 ABL1_HUMAN (45-524): 3.04e-174: 523: 41.10		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		487203 ABL2_HUMAN (7-524): 3.9e-173: 521: 38.64		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		368894 SRC_HUMAN (1-527): 0: 602: 65.74		ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20
+	Hs
		368834 YES_HUMAN (1-527): 0: 596: 67.83		ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20
+	Rn
		411266 SRC_RAT (1-527): 0: 606: 65.36		ESR1_RAT (378-904): 2.19e-130: 406: 20.94
+	Mm
		403414 SRC_MOUSE (1-527): 0: 608: 65.67		ESR1_MOUSE (378-904): 2.5e-129: 403: 21.30
+	Hs
		377007 FYN_HUMAN (1-527): 0: 607: 69.94		GCR_HUMAN (444-920): 1.2e-117: 378: 40.85
+	Hs
		377057 SRC_HUMAN (1-527): 0: 602: 65.74		GCR_HUMAN (444-920): 1.2e-117: 378: 40.85
+	Hs
		522762 SRC_HUMAN (1-527): 0: 602: 65.74		RXRA_HUMAN (392-902): 7.05e-120: 374: 19.84
+	Hs
		523091 SRC_HUMAN (1-527): 0: 602: 65.74		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Hs
		433435 YES_HUMAN (1-527): 0: 596: 67.83		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Hs
		414427 SRC_HUMAN (1-527): 0: 602: 65.74		PRGR_HUMAN (469-920): 4.71e-106: 352: 45.73
+	Hs
		487890 SRC_HUMAN (1-527): 0: 602: 65.74		RARA_HUMAN (460-902): 8.57e-110: 348: 19.87
+	Hs
		377006 LCK_HUMAN (1-526): 0: 559: 51.90		GCR_HUMAN (444-920): 1.2e-117: 378: 40.85