Interactor 1: FGR (P09769)
Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)
Gene: FGR

Interactor 2: STAT3 (P40763)
Signal transducer and activator of transcription 3 (Acute-phase response factor)
Gene: STAT3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.767

The method score is based on:

Property Details
Experiments 12244095, 21988832
Identification Methods pull down, two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH2, SH2~SH2, SH2~SH3_1
Common GO terms GO:0005102 - signaling receptor binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0019901 - protein kinase binding
GO:0030154 - cell differentiation
and 1 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 529
Hs

1 770
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Last updated: 15 Jul 2024