HitPredict

Interactor 1: FGR (P09769)
Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)
Gene: FGR

Interactor 2: DAB2 (P98082)
Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Differentially-expressed protein 2)
Gene: DAB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12473651
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030335 - positive regulation of cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 529 Hs			1 770
+	Hs
		412132 FYN_HUMAN (1-527): 0: 607: 69.94		DAB2_HUMAN (1-770): 3.91e-90: 301: 100.00
+	Hs
		522909 SRC_HUMAN (1-527): 0: 602: 65.74		DAB2_HUMAN (1-770): 3.91e-90: 301: 100.00
+	Mm
		403429 SRC_MOUSE (1-527): 0: 608: 65.67		DAB1_MOUSE (16-597): 6.31e-41: 160: 24.27
+	Mm
		763385 FYN_MOUSE (1-527): 0: 607: 69.76		DAB1_MOUSE (16-597): 6.31e-41: 160: 24.27
+	Hs
		253524 FYN_HUMAN (1-527): 0: 607: 69.94		CAPON_HUMAN (19-299): 8.52e-35: 141: 13.91
+	Mm
		403451 SRC_MOUSE (1-527): 0: 608: 65.67		SHC2_MOUSE (6-368): 1.03e-33: 138: 11.97
+	Mm
		956225 YES_MOUSE (1-527): 0: 586: 67.28		DAB1_MOUSE (16-597): 6.31e-41: 160: 24.27
+	Hs
		411643 LCK_HUMAN (1-526): 0: 559: 51.90		NUMB_HUMAN (22-635): 7.43e-47: 179: 14.20
+	Hs
		433649 LYN_HUMAN (1-524): 0: 553: 53.91		NUMB_HUMAN (22-635): 7.43e-47: 179: 14.20
+	Hs
		411911 LCK_HUMAN (1-526): 0: 559: 51.90		NUMBL_HUMAN (18-585): 6.55e-41: 161: 13.54
+	Hs
		434112 LYN_HUMAN (1-524): 0: 553: 53.91		NUMBL_HUMAN (18-585): 6.55e-41: 161: 13.54
+	Hs
		522749 SRC_HUMAN (1-527): 0: 602: 65.74		MUC1_HUMAN (320-766): 7.89e-22: 103: 14.16
+	Hs
		253523 LCK_HUMAN (1-526): 0: 559: 51.90		CAPON_HUMAN (19-299): 8.52e-35: 141: 13.91
+	Hs
		297808 LYN_HUMAN (1-524): 0: 553: 53.91		K0754_HUMAN (247-770): 7.02e-32: 136: 10.75
+	Dm
		337651 ABL_DROME (71-523): 2.21e-166: 514: 43.04		DAB_DROME (42-732): 1.16e-36: 151: 22.46
+	Hs
		411582 LCK_HUMAN (1-526): 0: 559: 51.90		MUC1_HUMAN (320-766): 7.89e-22: 103: 14.16
+	Hs
		433560 LYN_HUMAN (1-524): 0: 553: 53.91		MUC1_HUMAN (320-766): 7.89e-22: 103: 14.16
+	Hs
		203198 LCK_HUMAN (1-526): 0: 559: 51.90		SYNJ1_HUMAN (196-735): 1.47e-19: 96.5: 13.64
+	Ce
		106650 SRC1_CAEEL (1-527): 7.22e-177: 510: 46.06		CED6_CAEEL (5-428): 1.43e-35: 143: 16.47
+	Hs
		337335 ABL1_HUMAN (45-524): 3.04e-174: 523: 41.10		MUC1_HUMAN (320-766): 7.89e-22: 103: 14.16