HitPredict

Interactor 1: AST3 (P09774)
Achaete-scute complex protein T3 (Protein lethal of scute) (Lethal of sc)
Gene: l(1)sc

Interactor 2: EMC (P18491)
Protein extra-macrochaetae
Gene: EMC

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	7821225, unassigned4
Identification Methods	affinity chromatography technology, experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 257 Dm			1 199
+	Dm
		485888 AST5_DROME (74-256): 1.38e-45: 153: 39.15		EMC_DROME (1-199): 3.43e-112: 320: 100.00
+	Dm
		485922 AST4_DROME (27-257): 1.05e-43: 152: 27.74		EMC_DROME (1-199): 3.43e-112: 320: 100.00
+	Hs
		526742 MYF5_HUMAN (3-245): 5.38e-38: 135: 16.67		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Mm
		485951 MYOD1_MOUSE (3-237): 3.68e-37: 134: 15.04		Q6GTZ3_MOUSE (38-99): 8.25e-29: 106: 47.76
+	Hs
		524549 LYL1_HUMAN (59-216): 1.05e-31: 119: 22.09		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Hs
		526743 MYF5_HUMAN (3-245): 5.38e-38: 135: 16.67		ID2_HUMAN (38-103): 8.94e-25: 95.6: 41.67
+	Mm
		485939 MYOD1_MOUSE (3-237): 3.68e-37: 134: 15.04		ID2_MOUSE (38-103): 5.4e-25: 96.4: 43.06
+	Hs
		545945 MYOD1_HUMAN (3-248): 5.59e-33: 124: 15.41		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Hs
		524547 LYL1_HUMAN (59-216): 1.05e-31: 119: 22.09		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Hs
		814914 ASCL3_HUMAN (11-178): 6.31e-30: 112: 25.71		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Hs
		814909 FIGLA_HUMAN (34-186): 3.59e-28: 109: 27.33		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Hs
		545958 MYOD1_HUMAN (3-248): 5.59e-33: 124: 15.41		ID2_HUMAN (38-103): 8.94e-25: 95.6: 41.67
+	Hs
		780989 ASCL3_HUMAN (11-178): 6.31e-30: 112: 25.71		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Hs
		814916 NGN3_HUMAN (34-217): 3.43e-27: 105: 18.09		ID4_HUMAN (38-103): 2.02e-31: 113: 41.25
+	Hs
		526744 MYF5_HUMAN (3-245): 5.38e-38: 135: 16.67		ID3_HUMAN (38-97): 6.85e-20: 82.5: 36.67
+	Mm
		485938 MYOD1_MOUSE (3-237): 3.68e-37: 134: 15.04		ID3_MOUSE (38-97): 1.05e-19: 82.1: 36.67
+	Mm
		589139 TAL1_MOUSE (66-222): 3.81e-26: 105: 22.36		ID1_MOUSE (38-99): 5.12e-29: 107: 47.76
+	Hs
		780971 ASCL4_HUMAN (19-174): 6.73e-27: 104: 22.56		ID1_HUMAN (38-99): 7.16e-29: 106: 47.76
+	Hs
		545959 MYOD1_HUMAN (3-248): 5.59e-33: 124: 15.41		ID3_HUMAN (38-97): 6.85e-20: 82.5: 36.67
+	Hs
		524557 LYL1_HUMAN (59-216): 1.05e-31: 119: 22.09		ID3_HUMAN (38-97): 6.85e-20: 82.5: 36.67