HitPredict

Interactor 1: CDC16 (P09798)
Anaphase-promoting complex subunit CDC16 (Cell division control protein 16)
Gene: CDC16

Interactor 2: CDC27 (P38042)
Anaphase-promoting complex subunit CDC27 (Anaphase-promoting complex subunit 3) (Cell division control protein 27)
Gene: CDC27

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 9469814, 7925276, 8895471, 21107322, 21186364, 12609981, 16554755, 17459880, 37968396, 23751495, 12574115, 10318877, 12887895, 12402045, 15649358, 15060174, 16429126, 16275330, 17406682, 15797379 and 1 others

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Identification Methods coimmunoprecipitation, two hybrid, tandem affinity purification, pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC3~ANAPC3, ANAPC3~TPR_8, ANAPC3~TPR_12, TPR_1~TPR_12, TPR_12~TPR_8, ANAPC3~TPR_2, TPR_1~TPR_2, TPR_16~TPR_2, TPR_2~TPR_8, TPR_1~TPR_8, TPR_16~TPR_8, TPR_8~TPR_8
Common GO terms GO:0005680 - anaphase-promoting complex
GO:0005737 - cytoplasm
GO:0007346 - regulation of mitotic cell cycle
GO:0016567 - protein ubiquitination
GO:0031145 - anaphase-promoting complex-dependent catabolic process
and 2 others

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Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 840
Sc

1 758
+ Sc
+ Mm
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs
+ Sc
+ Dm
+ Hs
+ Hs
+ Hs
+ Xl
+ Hs
+ At

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Last updated: 15 Jul 2024