HitPredict

Interactor 1: PARP1 (P09874)
Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-) [Cleaved into: Poly [ADP-ribose] polymerase 1, processed C-terminus (Poly [ADP-ribose] polymerase 1, 89-kDa form); Poly [ADP-ribose] polymerase 1, processed N-terminus (NT-PARP-1) (Poly [ADP-ribose] polymerase 1, 24-kDa form) (Poly [ADP-ribose] polymerase 1, 28-kDa form)]
Gene: PARP1

Interactor 2: KPRA (Q14558)
Phosphoribosyl pyrophosphate synthase-associated protein 1 (PRPP synthase-associated protein 1) (39 kDa phosphoribosypyrophosphate synthase-associated protein) (PAP39)
Gene: PRPSAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1014 Hs			1 356
+	Hs
		225831 PARP1_HUMAN (1-1014): 0: 1362: 100.00		KPRB_HUMAN (1-356): 1.88e-168: 475: 78.43
+	Hs
		455279 PARP1_HUMAN (1-1014): 0: 1362: 100.00		PRPS1_HUMAN (7-354): 2.56e-168: 473: 42.98
+	Hs
		455033 PARP1_HUMAN (1-1014): 0: 1362: 100.00		PRPS2_HUMAN (7-354): 2.87e-166: 468: 43.27
+	Hs
		515889 PARPT_HUMAN (710-1006): 4.56e-65: 234: 15.84		PRPS2_HUMAN (7-354): 2.87e-166: 468: 43.27