Interactor 1: DPOLA (P09884)
DNA polymerase alpha catalytic subunit (EC 2.7.7.7) (DNA polymerase alpha catalytic subunit p180)
Gene: POLA1

Interactor 2: PRI1 (P49642)
DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49)
Gene: PRIM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.662

The method score is based on:

Property Details
Experiments 28514442, 33961781, 22593576
Identification Methods affinity chromatography technology, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005658 - alpha DNA polymerase:primase complex
GO:0006269 - DNA replication, synthesis of primer
GO:0006270 - DNA replication initiation
GO:0008270 - zinc ion binding
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1462
Hs

1 420
+ Mm
+ Sp
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024