Interactor 1: DPOLA (P09884)
DNA polymerase alpha catalytic subunit (EC 2.7.7.7) (DNA polymerase alpha catalytic subunit p180)
Gene: POLA1

Interactor 2: DPOA2 (Q14181)
DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit)
Gene: POLA2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 36652389, 8223465
Identification Methods cross-linking study, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_pol_E_B~zf-DNA_Pol, Pol_alpha_B_N~zf-DNA_Pol
Common GO terms GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005658 - alpha DNA polymerase:primase complex
GO:0005829 - cytosol
GO:0006260 - DNA replication
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1462
Hs

1 598
+ Mm
+ Dm
+ Ce
+ Sp
+ Sc
+ Sc
+ Sp
+ Hs
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024