Interactor 1: IFIT2 (P09913)
Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2) (ISG-54 K) (Interferon-induced 54 kDa protein) (IFI-54K) (P54)
Gene: IFIT2

Interactor 2: IFIT1 (P09914)
Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K) (P56)
Gene: IFIT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.889

The method score is based on:

Property Details
Experiments 28514442, 33961781, 21642987
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, molecular sieving
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains TPR_12~TPR_8, TPR_2~TPR_8, TPR_8~TPR_8
Common GO terms GO:0003723 - RNA binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009615 - response to virus
GO:0032091 - negative regulation of protein binding
and 2 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 472
Hs

1 478
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Last updated: 15 Jul 2024