HitPredict

Interactor 1: IFIT1 (P09914)
Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K) (P56)
Gene: IFIT1

Interactor 2: NUCL (P19338)
Nucleolin (Protein C23)
Gene: NCL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21642987
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 478 Hs			1 710
+	Hs
		174613 OGT1_HUMAN (8-321): 3.8e-43: 165: 14.33		NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00
+	Hs
		456254 IFIT1_HUMAN (1-478): 1.64e-96: 300: 100.00		PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55
+	Hs
		456279 IFIT1_HUMAN (1-478): 1.64e-96: 300: 100.00		PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88
+	Hs
		157425 IFIT3_HUMAN (217-471): 5.16e-11: 66.8: 12.73		NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00
+	Hs
		174583 OGT1_HUMAN (8-321): 3.8e-43: 165: 14.33		PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55
+	Hs
		174849 OGT1_HUMAN (8-321): 3.8e-43: 165: 14.33		PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88
+	Sc
		376611 CYC8_YEAST (306-473): 3.59e-15: 80.3: 14.29		PABP_YEAST (181-555): 3.61e-53: 194: 17.47
+	Sc
		376779 TOM71_YEAST (49-475): 1.67e-10: 65.3: 11.63		PABP_YEAST (181-555): 3.61e-53: 194: 17.47
+	Hs
		157420 IFIT3_HUMAN (217-471): 5.16e-11: 66.8: 12.73		PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55
+	Hs
		157449 IFIT3_HUMAN (217-471): 5.16e-11: 66.8: 12.73		PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88
+	Hs
		456204 IFIT2_HUMAN (169-471): 1.95e-10: 64.8: 12.06		PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55
+	Mm
		665754 CTR9_MOUSE (227-477): 1.29e-09: 62.9: 12.83		PABP1_MOUSE (222-482): 5.43e-43: 167: 15.55
+	Hs
		456227 IFIT2_HUMAN (169-471): 1.95e-10: 64.8: 12.06		PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88