Interactor 1: IFIT1 (P09914)
Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K) (P56)
Gene: IFIT1

Interactor 2: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 32877691
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0045071 - negative regulation of viral genome replication
GO:0051607 - defense response to virus
GO:0071360 - cellular response to exogenous dsRNA
GO:0140374 - antiviral innate immune response
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 478
Hs

1 540
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024