HitPredict

Interactor 1: UCHL1 (P09936)
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1) (EC 3.4.19.12) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5) (Ubiquitin thioesterase L1)
Gene: UCHL1

Interactor 2: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 223 Hs			1 216
+	Hs
		548126 UCHL3_HUMAN (2-222): 2.74e-100: 292: 54.43		RAB1B_HUMAN (4-195): 1.12e-80: 240: 28.72
+	Hs
		918921 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		RAB1A_HUMAN (1-196): 3.67e-82: 244: 28.00
+	Hs
		1267154 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		RAB1B_HUMAN (4-195): 1.12e-80: 240: 28.72
+	Hs
		919192 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		845385 UCHL5_HUMAN (2-220): 2.67e-99: 293: 21.68		RAB7A_HUMAN (8-166): 7.44e-29: 108: 33.13
+	Hs
		548076 UCHL3_HUMAN (2-222): 2.74e-100: 292: 54.43		RAB7A_HUMAN (8-166): 7.44e-29: 108: 33.13
+	Hs
		895530 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		RAB10_HUMAN (11-177): 3.9e-29: 109: 33.14
+	Hs
		845123 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		RAB7A_HUMAN (8-166): 7.44e-29: 108: 33.13