HitPredict

Interactor 1: UCHL1 (P09936)
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1) (EC 3.4.19.12) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5) (Ubiquitin thioesterase L1)
Gene: UCHL1

Interactor 2: CBX1 (P83916)
Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta)
Gene: CBX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	16169070, 32814053
Identification Methods	two hybrid, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 223 Hs			1 185
+	Hs
		1027156 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		CBX3_HUMAN (1-177): 2.11e-63: 195: 69.49
+	Hs
		949856 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		CBX1_HUMAN (1-185): 2.21e-62: 193: 100.00
+	Hs
		800477 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		CBX5_HUMAN (1-183): 9.59e-60: 186: 57.45
+	Hs
		327870 UCHL5_HUMAN (2-220): 2.67e-99: 293: 21.68		CBX7_HUMAN (12-114): 5.3e-30: 112: 27.18