HitPredict

Interactor 1: UCHL1 (P09936)
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1) (EC 3.4.19.12) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5) (Ubiquitin thioesterase L1)
Gene: UCHL1

Interactor 2: TRI54 (Q9BYV2)
Tripartite motif-containing protein 54 (Muscle-specific RING finger protein) (MuRF) (Muscle-specific RING finger protein 3) (MuRF-3) (MuRF3) (RING finger protein 30)
Gene: TRIM54

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	22626734
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 223 Hs			1 358
+	Hs
		1317499 UCHL5_HUMAN (2-220): 2.67e-99: 293: 21.68		TRI54_HUMAN (1-358): 7.84e-87: 267: 100.00
+	Hs
		548123 UCHL3_HUMAN (2-222): 2.74e-100: 292: 54.43		TRI54_HUMAN (1-358): 7.84e-87: 267: 100.00
+	Hs
		456497 UCHL1_HUMAN (1-223): 2.52e-103: 299: 100.00		RO52_HUMAN (11-358): 3.3e-75: 241: 17.14
+	Hs
		1317550 UCHL5_HUMAN (2-220): 2.67e-99: 293: 21.68		TRI55_HUMAN (1-328): 3.79e-76: 246: 65.24
+	Hs
		548124 UCHL3_HUMAN (2-222): 2.74e-100: 292: 54.43		TRI55_HUMAN (1-328): 3.79e-76: 246: 65.24
+	Hs
		456621 UCHL1_HUMAN (1-223): 2.52e-103: 299: 100.00		TRI63_HUMAN (8-328): 1.02e-74: 236: 60.44
+	Hs
		1282081 UCHL5_HUMAN (2-220): 2.67e-99: 293: 21.68		TRI63_HUMAN (8-328): 1.02e-74: 236: 60.44
+	Hs
		548114 UCHL3_HUMAN (2-222): 2.74e-100: 292: 54.43		TRI63_HUMAN (8-328): 1.02e-74: 236: 60.44
+	Hs
		537150 UCHL5_HUMAN (2-220): 2.67e-99: 293: 21.68		TRI27_HUMAN (11-358): 2.55e-69: 227: 17.30
+	Hs
		536719 UCHL3_HUMAN (2-222): 2.74e-100: 292: 54.43		TRI27_HUMAN (11-358): 2.55e-69: 227: 17.30
+	Hs
		1190465 UCHL5_HUMAN (2-220): 2.67e-99: 293: 21.68		TRI46_HUMAN (2-355): 2.48e-63: 216: 23.13
+	Hs
		456595 UCHL1_HUMAN (1-223): 2.52e-103: 299: 100.00		TRI67_HUMAN (121-332): 1.86e-59: 206: 26.42
+	Hs
		1172444 UCHL5_HUMAN (2-220): 2.67e-99: 293: 21.68		TRI67_HUMAN (121-332): 1.86e-59: 206: 26.42
+	Hs
		548108 UCHL3_HUMAN (2-222): 2.74e-100: 292: 54.43		TRI67_HUMAN (121-332): 1.86e-59: 206: 26.42
+	Hs
		585024 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		RO52_HUMAN (11-358): 3.3e-75: 241: 17.14
+	Hs
		1267066 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		TRI63_HUMAN (8-328): 1.02e-74: 236: 60.44
+	Hs
		1171040 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		TRI67_HUMAN (121-332): 1.86e-59: 206: 26.42
+	Hs
		175701 BAP1_HUMAN (3-220): 2.36e-78: 250: 22.27		TRI18_HUMAN (46-333): 8.71e-60: 205: 22.49