Interactor 1: FURIN (P09958)
Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE)
Gene: FURIN
Interactor 2: ISK5 (Q9NQ38)
Serine protease inhibitor Kazal-type 5 (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Cleaved into: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665]
Gene: SPINK5
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12915442 |
| Identification Methods | cleavage assay |
| Interaction Type | protein cleavage |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Kazal_1~Peptidase_S8 |
| Common GO terms | GO:0004867 - serine-type endopeptidase inhibitor activity GO:0005576 - extracellular region GO:0005783 - endoplasmic reticulum GO:0030198 - extracellular matrix organization |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Dm |   |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
