HitPredict

Interactor 1: NMDZ1 (A0A1L8F5J9)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)
Gene: grin1

Interactor 2: NMDE2 (A7XY94)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B)
Gene: grin2b

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.747

The method score is based on:

Property Details
Experiments 25008524
Identification Methods pull down, x-ray crystallography, molecular sieving
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan~SBP_bac_3, Lig_chan-Glu_bd~Lig_chan-Glu_bd, Lig_chan-Glu_bd~SBP_bac_3, SBP_bac_3~SBP_bac_3
Common GO terms GO:0004972 - NMDA glutamate receptor activity
GO:0005886 - plasma membrane
GO:0010043 - response to zinc ion
GO:0017146 - NMDA selective glutamate receptor complex
GO:0045211 - postsynaptic membrane
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 903
Xl

1 1448
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Last updated: 15 Jul 2024