Interactor 1: CLPP (P0A6G7)
ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) (Caseinolytic protease) (Endopeptidase Clp) (Heat shock protein F21.5) (Protease Ti)
Gene: CLPP

Interactor 2: CLPX (P0A6H1)
ATP-dependent Clp protease ATP-binding subunit ClpX (ATP-dependent unfoldase ClpX)
Gene: CLPX

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.857

The method score is based on:

Property Details
Experiments 16606699, 25866879, 19368884
Identification Methods affinity chromatography technology, classical fluorescence spectroscopy, enzymatic study, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_2~CLP_protease
Common GO terms GO:0004176 - ATP-dependent peptidase activity
GO:0005829 - cytosol
GO:0009368 - endopeptidase Clp complex
GO:0009376 - HslUV protease complex
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 207
Ec

1 424
+ Hs
+ Bs
+ At
+ At
+ Mt
+ Dm

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Last updated: 15 Jul 2024