HitPredict

Interactor 1: CLPX (P0A6H1)
ATP-dependent Clp protease ATP-binding subunit ClpX (ATP-dependent unfoldase ClpX)
Gene: CLPX

Interactor 2: CLPX (P0A6H1)
ATP-dependent Clp protease ATP-binding subunit ClpX (ATP-dependent unfoldase ClpX)
Gene: CLPX

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.915

The method score is based on:

Property Details
Experiments 24561554, 25866879, 19914167, 23622246
Identification Methods two hybrid, molecular sieving, comigration in sds page, cross-linking study, x-ray crystallography, fluorescence technology, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_2~AAA_2, AAA_2~ClpB_D2-small, ClpB_D2-small~ClpB_D2-small, zf-C4_ClpX~zf-C4_ClpX
Common GO terms GO:0002020 - protease binding
GO:0004176 - ATP-dependent peptidase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
and 11 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 424
Ec

1 424
+ Ec
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs
+ Dm
+ Dm
+ Dm
+ Ce
+ Dm
+ Hs
+ Af

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024