HitPredict

Interactor 1: A0A1W2PNV4 (A0A1W2PNV4)
Actin-related protein 2/3 complex subunit 1A
Gene: A0A1W2PNV4

Interactor 2: ARP2 (P61160)
Actin-related protein 2 (Actin-like protein 2)
Gene: ACTR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Actin~WD40
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005885 - Arp2/3 protein complex GO:0034314 - Arp2/3 complex-mediated actin nucleation GO:0051015 - actin filament binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 684 Hs			1 394
+	Hs
		168764 ARC1B_HUMAN (248-565): 4.36e-17: 85.6: 11.88		ARP2_HUMAN (1-394): 0: 815: 100.00
+	Hs
		896946 ARC1A_HUMAN (165-511): 9.26e-11: 65.9: 9.19		ARP2_HUMAN (1-394): 0: 815: 100.00
+	Sc
		689335 ARPC1_YEAST (1-367): 1.48e-93: 296: 37.90		ARP2_YEAST (9-390): 0: 549: 67.89
+	Sp
		945008 ARPC1_SCHPO (5-367): 3.3e-92: 292: 42.20		ARP2_SCHPO (9-390): 0: 537: 66.23
+	Dm
		332992 O97182_DROME (89-508): 3.51e-11: 67.5: 10.71		ARP2_DROME (1-389): 0: 696: 81.47
+	Hs
		254068 WDR1_HUMAN (406-671): 3.24e-24: 109: 11.44		ACTB_HUMAN (1-388): 0: 574: 46.65
+	Hs
		254073 WDR1_HUMAN (406-671): 3.24e-24: 109: 11.44		ACTG_HUMAN (3-388): 0: 573: 46.37
+	Hs
		254075 WDR1_HUMAN (406-671): 3.24e-24: 109: 11.44		ACTC_HUMAN (2-388): 0: 569: 46.51
+	Hs
		168762 ARC1B_HUMAN (248-565): 4.36e-17: 85.6: 11.88		ACTB_HUMAN (1-388): 0: 574: 46.65
+	Hs
		168775 ARC1B_HUMAN (248-565): 4.36e-17: 85.6: 11.88		ACTG_HUMAN (3-388): 0: 573: 46.37
+	Hs
		891938 ARC1A_HUMAN (165-511): 9.26e-11: 65.9: 9.19		ACTB_HUMAN (1-388): 0: 574: 46.65
+	Dm
		332994 O97182_DROME (89-508): 3.51e-11: 67.5: 10.71		ACT3_DROME (1-388): 0: 571: 45.36