HitPredict

Interactor 1: DPO3B (P0A988)
Beta sliding clamp (Beta clamp) (Sliding clamp) (Beta-clamp processivity factor) (DNA polymerase III beta sliding clamp subunit)
Gene: dnaN

Interactor 2: DPO3B (P0A988)
Beta sliding clamp (Beta clamp) (Sliding clamp) (Beta-clamp processivity factor) (DNA polymerase III beta sliding clamp subunit)
Gene: dnaN

Species: Escherichia coli K-12

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.942

The method score is based on:

Property Details
Experiments 24561554, 19834901, 1349852, 23435564, 16858726, 24627523
Identification Methods two hybrid, two hybrid array, x-ray crystallography, molecular sieving, mass spectrometry studies of complexes, blue native page
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_pol3_beta~DNA_pol3_beta, DNA_pol3_beta~DNA_pol3_beta_2, DNA_pol3_beta~DNA_pol3_beta_3, DNA_pol3_beta_2~DNA_pol3_beta_2, DNA_pol3_beta_2~DNA_pol3_beta_3, DNA_pol3_beta_3~DNA_pol3_beta_3
Common GO terms GO:0003677 - DNA binding
GO:0003887 - DNA-directed DNA polymerase activity
GO:0005829 - cytosol
GO:0006261 - DNA-templated DNA replication
GO:0006271 - DNA strand elongation involved in DNA replication
and 11 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 366
Ec

1 366
+ Mt
+ Ms
+ Bs
+ Mp
+ Hp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024