Interactor 1: SERA (P0A9T0)
D-3-phosphoglycerate dehydrogenase (PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399)
Gene: SERA

Interactor 2: SERA (P0A9T0)
D-3-phosphoglycerate dehydrogenase (PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399)
Gene: SERA

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 7719856
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 2-Hacid_dh~2-Hacid_dh, 2-Hacid_dh~2-Hacid_dh_C, 2-Hacid_dh~ACT, 2-Hacid_dh_C~2-Hacid_dh_C, ACT~ACT
Common GO terms GO:0004617 - phosphoglycerate dehydrogenase activity
GO:0005829 - cytosol
GO:0006564 - L-serine biosynthetic process
GO:0047545 - 2-hydroxyglutarate dehydrogenase activity
GO:0070403 - NAD+ binding
and 2 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 410
Ec

1 410
+ Sc
+ Sc
+ Sc
+ At
+ Hs
+ Cj
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Ec
+ Dm
+ Sp
+ Hp

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Last updated: 15 Jul 2024