HitPredict

Interactor 1: FTSH (P0AAI3)
ATP-dependent zinc metalloprotease FtsH (EC 3.4.24.-) (Cell division protease FtsH)
Gene: FTSH

Interactor 2: HFLC (P0ABC3)
Modulator of FtsH protease HflC
Gene: HFLC

Species: Escherichia coli K-12

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.706

Property	Details
Experiments	29176613, 19402753, 15690043, 20599668, 18387365
Identification Methods	affinity chromatography technology, tandem affinity purification, pull down, cross-linking study
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0098796 - membrane protein complex GO:0098797 - plasma membrane protein complex
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 644 Ec			1 334
+	Ec
		465868 FTSH_ECOLI (1-644): 0: 574: 100.00		HFLK_ECOLI (20-315): 2.21e-54: 185: 19.46
+	Hs
		1303127 YMEL1_HUMAN (410-643): 5.5e-35: 143: 12.80		STML2_HUMAN (20-321): 5.23e-54: 182: 17.56