HitPredict

Interactor 1: AROG (P0AB91)
Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive (EC 2.5.1.54) (3-deoxy-D-arabino-heptulosonate 7-phosphate synthase) (DAHP synthase) (Phospho-2-keto-3-deoxyheptonate aldolase)
Gene: AROG

Interactor 2: AROG (P0AB91)
Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive (EC 2.5.1.54) (3-deoxy-D-arabino-heptulosonate 7-phosphate synthase) (DAHP synthase) (Phospho-2-keto-3-deoxyheptonate aldolase)
Gene: AROG

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.820

The method score is based on:

Property Details
Experiments 10425687, 26682
Identification Methods x-ray crystallography, molecular sieving, cosedimentation in solution, protein cross-linking with a bifunctional reagent, comigration in non denaturing gel electrophoresis
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DAHP_synth_1~DAHP_synth_1
Common GO terms GO:0003849 - 3-deoxy-7-phosphoheptulonate synthase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008652 - amino acid biosynthetic process
GO:0009073 - aromatic amino acid family biosynthetic process
and 1 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 350
Ec

1 350
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024