Interactor 1: MBHL (P0ACD8)
Hydrogenase-1 large chain (HYD1) (EC 1.12.99.6) (Membrane-bound hydrogenase 1 large subunit) (NiFe hydrogenase)
Gene: hyaB

Interactor 2: MBHT (P69741)
Hydrogenase-2 small chain (HYD2) (EC 1.12.99.6) (Membrane-bound hydrogenase 2 small subunit) (NiFe hydrogenase)
Gene: hybO

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 29176613, 16858726
Identification Methods affinity chromatography technology, blue native page
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains NiFe_hyd_SSU_C~NiFeSe_Hases, NiFeSe_Hases~Oxidored_q6
Common GO terms GO:0008901 - ferredoxin hydrogenase activity
GO:0009055 - electron transfer activity
GO:0009061 - anaerobic respiration
GO:0016020 - membrane
GO:0033748 - hydrogenase (acceptor) activity
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 597
Ec

1 372
+ Ec
+ Nv
+ Nv

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024