HitPredict

Interactor 1: HINT (P0ACE7)
Purine nucleoside phosphoramidase (EC 3.9.1.-) (Histidine triad nucleotide binding protein HinT) (HIT protein)
Gene: HINT

Interactor 2: HINT (P0ACE7)
Purine nucleoside phosphoramidase (EC 3.9.1.-) (Histidine triad nucleotide binding protein HinT) (HIT protein)
Gene: HINT

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	24561554
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HIT~HIT
Common GO terms	GO:0000166 - nucleotide binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0042803 - protein homodimerization activity GO:0043530 - adenosine 5'-monophosphoramidase activity and 1 others more... GO:0055130 - D-alanine catabolic process
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 119 Ec			1 119
+	Hs
		1315002 HINT2_HUMAN (2-110): 5.32e-43: 140: 46.79		HINT2_HUMAN (2-110): 5.32e-43: 140: 46.79
+	Ss
		938419 YHIT_SYNY3 (1-111): 2.52e-41: 134: 49.55		YHIT_SYNY3 (1-111): 2.52e-41: 134: 49.55
+	Hs
		834470 HINT1_HUMAN (4-110): 1.29e-40: 132: 47.66		HINT1_HUMAN (4-110): 1.29e-40: 132: 47.66
+	Hs
		834509 HINT1_HUMAN (4-110): 1.29e-40: 132: 47.66		HINT3_HUMAN (2-111): 4.16e-29: 105: 23.01
+	Sc
		979402 HNT1_YEAST (1-108): 1.42e-34: 118: 33.33		HNT1_YEAST (1-108): 1.42e-34: 118: 33.33
+	Mp
		939927 YHIT_MYCPN (2-111): 2.26e-34: 117: 26.79		YHIT_MYCPN (2-111): 2.26e-34: 117: 26.79
+	Sp
		834524 APH1_SCHPO (1-111): 5e-33: 115: 23.42		APH1_SCHPO (1-111): 5e-33: 115: 23.42
+	Sc
		834522 HNT2_YEAST (1-111): 2.16e-32: 114: 19.64		HNT2_YEAST (1-111): 2.16e-32: 114: 19.64
+	Cj
		1008745 Q0PA00_CAMJE (1-110): 2.81e-33: 113: 38.18		Q0PA00_CAMJE (1-110): 2.81e-33: 113: 38.18
+	Sp
		293722 HNT1_SCHPO (4-107): 1.57e-32: 112: 26.92		HNT1_SCHPO (4-107): 1.57e-32: 112: 26.92
+	Ca
		1124144 HNT1_CANAL (3-108): 1.09e-31: 111: 29.46		HNT1_CANAL (3-108): 1.09e-31: 111: 29.46
+	Hp
		190569 O25440_HELPY (2-108): 7.72e-28: 101: 21.43		O25440_HELPY (2-108): 7.72e-28: 101: 21.43
+	At
		99267 FHIT_ARATH (15-108): 1.02e-26: 99.2: 23.96		FHIT_ARATH (15-108): 1.02e-26: 99.2: 23.96
+	Hs
		834547 FHIT_HUMAN (15-108): 1.1e-24: 93.1: 21.28		FHIT_HUMAN (15-108): 1.1e-24: 93.1: 21.28
+	Zm
		26898 A0A1D6JB03_MAIZE (1-106): 2.28e-22: 88: 24.62		A0A1D6JB03_MAIZE (1-106): 2.28e-22: 88: 24.62