HitPredict

Interactor 1: CUSR (P0ACZ8)
Transcriptional regulatory protein CusR
Gene: CUSR

Interactor 2: CUSS (P77485)
Sensor histidine kinase CusS (EC 2.7.13.3)
Gene: CUSS

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.80	0.677

Property	Details
Experiments	15522865, 24627523
Identification Methods	affinity chromatography technology, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HATPase_c~Response_reg, HisKA~Response_reg
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 227 Ec			1 480
+	Ss
		1122361 Q55942_SYNY3 (1-222): 7.58e-75: 227: 40.00		Q55941_SYNY3 (252-478): 3.07e-72: 237: 34.91
+	Ec
		439475 PHOB_ECOLI (2-222): 7.31e-82: 245: 33.18		PHOR_ECOLI (203-479): 4.86e-62: 210: 31.54
+	Mx
		1091479 Q1DCL7_MYXXD (3-222): 4.9e-78: 235: 36.16		Q1D333_MYXXD (104-479): 3.01e-64: 216: 22.34
+	Cv
		1308005 Q9ABD5_CAUVC (3-223): 8.65e-79: 237: 37.67		Q9ABD9_CAUVC (255-479): 3.53e-63: 214: 26.85
+	Ss
		937545 P72948_SYNY3 (2-225): 1.03e-77: 235: 35.62		Q55475_SYNY3 (77-479): 1.11e-63: 213: 23.98
+	Mx
		1091248 Q1D1K9_MYXXD (2-221): 3.21e-74: 225: 34.09		Q1CVV2_MYXXD (215-478): 3.15e-61: 216: 26.77
+	Mx
		1091444 Q1D1K9_MYXXD (2-221): 3.21e-74: 225: 34.09		Q1D333_MYXXD (104-479): 3.01e-64: 216: 22.34
+	Mx
		1091452 Q1D4T4_MYXXD (3-224): 3.1e-70: 216: 33.19		Q1D1W0_MYXXD (186-478): 2.71e-67: 225: 27.03
+	Mx
		1091457 Q1D8M8_MYXXD (3-223): 2.35e-70: 216: 37.67		Q1D1W0_MYXXD (186-478): 2.71e-67: 225: 27.03
+	Ss
		938123 RPPA_SYNY3 (1-225): 3.83e-72: 221: 31.06		HIK2_SYNY3 (101-478): 9.25e-65: 217: 17.79
+	Mx
		1091327 Q1D8M8_MYXXD (3-223): 2.35e-70: 216: 37.67		Q1CWW4_MYXXD (155-479): 2.67e-63: 221: 20.30
+	Mx
		1091475 Q1D8M8_MYXXD (3-223): 2.35e-70: 216: 37.67		Q1D333_MYXXD (104-479): 3.01e-64: 216: 22.34
+	Ss
		1122356 RPPA_SYNY3 (1-225): 3.83e-72: 221: 31.06		RPPB_SYNY3 (49-479): 9.41e-61: 207: 21.74
+	Ec
		940183 HPRR_ECOLI (1-221): 2.38e-71: 218: 50.68		HPRS_ECOLI (162-479): 1.53e-61: 209: 29.78
+	Mx
		1091534 Q1D8M8_MYXXD (3-223): 2.35e-70: 216: 37.67		Q1D6S5_MYXXD (214-480): 1.43e-23: 104: 29.71
+	Mx
		1091447 Q1D1K9_MYXXD (2-221): 3.21e-74: 225: 34.09		Q1DDJ8_MYXXD (262-479): 1.3e-16: 84.3: 31.70
+	Mx
		1091561 Q1D8M8_MYXXD (3-223): 2.35e-70: 216: 37.67		Q1DDJ8_MYXXD (262-479): 1.3e-16: 84.3: 31.70
+	Ec
		465607 OMPR_ECOLI (2-226): 1.28e-71: 220: 37.07		ENVZ_ECOLI (201-471): 4.95e-15: 79: 27.56
+	Mx
		1091565 Q1DCL7_MYXXD (3-222): 4.9e-78: 235: 36.16		Q1D948_MYXXD (265-479): 1.33e-09: 62.8: 26.91
+	Mx
		1091559 Q1D8M8_MYXXD (3-223): 2.35e-70: 216: 37.67		Q1D948_MYXXD (265-479): 1.33e-09: 62.8: 26.91