Interactor 1: KPYK1 (P0AD61)
Pyruvate kinase I (EC 2.7.1.40) (PK-1)
Gene: pykF

Interactor 2: KPYK1 (P0AD61)
Pyruvate kinase I (EC 2.7.1.40) (PK-1)
Gene: pykF

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 8591049, 16858726
Identification Methods x-ray crystallography, blue native page
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK~PK, PK~PK_C, PK_C~PK_C
Common GO terms GO:0000287 - magnesium ion binding
GO:0004743 - pyruvate kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 8 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 470
Ec

1 470
+ Hs
+ Hs
+ Oc
+ Ce
+ Ce
+ Ce
+ Ce
+ Sc
+ Sc
+ At
+ At
+ Zm

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Last updated: 15 Jul 2024