HitPredict

Interactor 1: GYRA (P0AES4)
DNA gyrase subunit A (EC 5.6.2.2)
Gene: GYRA

Interactor 2: GYRA (P0AES4)
DNA gyrase subunit A (EC 5.6.2.2)
Gene: GYRA

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.894

The method score is based on:

Property Details
Experiments 15698572, 19834901, 19647513, 16858726
Identification Methods molecular sieving, cosedimentation in solution, x ray scattering, two hybrid array, blue native page
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_gyraseA_C~DNA_gyraseA_C, DNA_topoisoIV~DNA_topoisoIV
Common GO terms GO:0003677 - DNA binding
GO:0003918 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 - ATP binding
GO:0005694 - chromosome
GO:0005737 - cytoplasm
and 11 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 875
Ec

1 875
+ Ec
+ Zm
+ Hs
+ Hs
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024