Interactor 1: GYRA (P0AES4)
DNA gyrase subunit A (EC 5.6.2.2)
Gene: GYRA
Interactor 2: GYRB (P0AES6)
DNA gyrase subunit B (EC 5.6.2.2) (Type IIA topoisomerase subunit GyrB)
Gene: GYRB
Species: Escherichia coli K-12
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 1.00 | 0.759 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15690043, unassigned104 |
| Identification Methods | tandem affinity purification, comigration in non denaturing gel electrophoresis, pull down |
| Interaction Type | association, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DNA_gyraseB~DNA_topoisoIV, DNA_gyraseB_C~DNA_topoisoIV, DNA_topoisoIV~GyrB_insert, DNA_topoisoIV~Toprim |
| Common GO terms | GO:0003677 - DNA binding GO:0003918 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity GO:0005524 - ATP binding GO:0005694 - chromosome GO:0005737 - cytoplasm and 9 others more... |
| Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
