HitPredict

Interactor 1: RSEA (P0AFX7)
Anti-sigma-E factor RseA (Regulator of SigE) (Sigma-E anti-sigma factor RseA) (Sigma-E factor negative regulatory protein)
Gene: RSEA

Interactor 2: RSEB (P0AFX9)
Sigma-E factor regulatory protein RseB
Gene: RSEB

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.90	0.828

Property	Details
Experiments	17496148, 20512978, 19103591
Identification Methods	x ray scattering, pull down, x-ray crystallography, cross-linking study
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	MucB_RseB~RseA_C, MucB_RseB_C~RseA_C
Common GO terms	GO:0005886 - plasma membrane GO:0045892 - negative regulation of DNA-templated transcription GO:1903865 - sigma factor antagonist complex
Homologous interactions	0