HitPredict

Interactor 1: RSEA (P0AFX7)
Anti-sigma-E factor RseA (Regulator of SigE) (Sigma-E anti-sigma factor RseA) (Sigma-E factor negative regulatory protein)
Gene: RSEA

Interactor 2: RPOE (P0AGB6)
ECF RNA polymerase sigma-E factor (RNA polymerase sigma-E factor) (Sigma-24)
Gene: RPOE

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.90	0.753

Property	Details
Experiments	24561554, 29176613
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RseA_N~Sigma70_r2, RseA_N~Sigma70_r4_2
Common GO terms	GO:0005886 - plasma membrane GO:0045892 - negative regulation of DNA-templated transcription GO:1903865 - sigma factor antagonist complex
Homologous interactions	0