Interactor 1: RELA (P0AG20)
GTP pyrophosphokinase (EC 2.7.6.5) ((p)ppGpp synthase) (ATP:GTP 3'-pyrophosphotransferase) (ppGpp synthase I)
Gene: RELA

Interactor 2: RELA (P0AG20)
GTP pyrophosphokinase (EC 2.7.6.5) ((p)ppGpp synthase) (ATP:GTP 3'-pyrophosphotransferase) (ppGpp synthase I)
Gene: RELA

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.590

The method score is based on:

Property Details
Experiments 18996989
Identification Methods adenylate cyclase complementation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ACT_4~ACT_4, HD_4~HD_4, HD_4~RelA_SpoT, RelA_SpoT~RelA_SpoT, RelA_SpoT~TGS, TGS~TGS
Common GO terms GO:0005524 - ATP binding
GO:0005525 - GTP binding
GO:0005886 - plasma membrane
GO:0008728 - GTP diphosphokinase activity
GO:0008893 - guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity
and 6 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 744
Ec

1 744
+ Pa
+ Bs
+ Ec
+ Pa
+ Hp
+ Cj
+ Dm
+ Ss

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Last updated: 15 Jul 2024