Interactor 1: SPOT (P0AG24)
Bifunctional (p)ppGpp synthase/hydrolase SpoT [Includes: GTP pyrophosphokinase (EC 2.7.6.5) ((p)ppGpp synthase) (ATP:GTP 3'-pyrophosphotransferase) (Stringent response-like protein) (ppGpp synthase II); Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase)]
Gene: SPOT
Interactor 2: SPOT (P0AG24)
Bifunctional (p)ppGpp synthase/hydrolase SpoT [Includes: GTP pyrophosphokinase (EC 2.7.6.5) ((p)ppGpp synthase) (ATP:GTP 3'-pyrophosphotransferase) (Stringent response-like protein) (ppGpp synthase II); Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase)]
Gene: SPOT
Species: Escherichia coli K-12
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.34 | 1.00 | 0.590 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18996989 |
| Identification Methods | adenylate cyclase complementation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ACT_4~ACT_4, HD_4~HD_4, HD_4~RelA_SpoT, RelA_SpoT~RelA_SpoT, RelA_SpoT~TGS, TGS~TGS |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008728 - GTP diphosphokinase activity GO:0008893 - guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity GO:0015949 - nucleobase-containing small molecule interconversion and 5 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
