HitPredict

Interactor 1: A0A583ZBW8 (A0A583ZBW8)
HLA-C protein
Gene: HLA-C

Interactor 2: KI2S4 (P43632)
Killer cell immunoglobulin-like receptor 2DS4 (CD158 antigen-like family member I) (Natural killer-associated transcript 8) (NKAT-8) (P58 natural killer cell receptor clones CL-39/CL-17) (p58 NK receptor CL-39/CL-17) (CD antigen CD158i)
Gene: KIR2DS4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	19858347
Identification Methods	affinity chromatography technology
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~ig, MHC_I~ig
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 366 Hs			1 304
+	Hs
		798280 Q5S3G3_HUMAN (1-365): 1.02e-178: 501: 82.19		KI2S4_HUMAN (1-304): 2.69e-114: 333: 100.00
+	Hs
		798195 Q5S3G3_HUMAN (1-365): 1.02e-178: 501: 82.19		KI2L3_HUMAN (1-304): 4.35e-106: 314: 88.16
+	Hs
		798194 Q5RIP0_HUMAN (1-366): 8.47e-173: 487: 94.81		KI2L3_HUMAN (1-304): 4.35e-106: 314: 88.16
+	Hs
		798173 Q5RIP0_HUMAN (1-366): 8.47e-173: 487: 94.81		KI2L2_HUMAN (1-303): 6.82e-104: 309: 88.12
+	Hs
		798148 Q5RIP0_HUMAN (1-366): 8.47e-173: 487: 94.81		KI2L1_HUMAN (1-303): 1.4e-103: 308: 87.46
+	Hs
		798171 Q5D1W8_HUMAN (1-366): 1.18e-170: 481: 93.44		KI2L2_HUMAN (1-303): 6.82e-104: 309: 88.12
+	Hs
		798146 Q5D1W8_HUMAN (1-366): 1.18e-170: 481: 93.44		KI2L1_HUMAN (1-303): 1.4e-103: 308: 87.46
+	Hs
		382484 HLAA_HUMAN (1-365): 1.04e-179: 504: 81.92		LIRB4_HUMAN (1-304): 1.07e-68: 221: 29.51
+	Hs
		1060406 Q95J06_HUMAN (1-365): 0: 514: 80.55		KI3S1_HUMAN (1-246): 2.84e-56: 188: 35.74
+	Hs
		47499 HLAA_HUMAN (1-365): 1.04e-179: 504: 81.92		A0A8I5QEB2_HUMAN (1-246): 1.17e-58: 194: 40.16
+	Hs
		382420 HLAA_HUMAN (1-365): 1.04e-179: 504: 81.92		KI3S1_HUMAN (1-246): 2.84e-56: 188: 35.74
+	Hs
		382341 HLAA_HUMAN (1-365): 1.04e-179: 504: 81.92		KI3L2_HUMAN (1-246): 1.43e-54: 185: 38.96
+	Hs
		798244 Q5S3G3_HUMAN (1-365): 1.02e-178: 501: 82.19		KI3L2_HUMAN (1-246): 1.43e-54: 185: 38.96
+	Hs
		1060403 Q5SUL5_HUMAN (1-365): 3.61e-176: 495: 80.27		KI3S1_HUMAN (1-246): 2.84e-56: 188: 35.74
+	Hs
		1245576 Q95J06_HUMAN (1-365): 0: 514: 80.55		LIRB1_HUMAN (21-258): 8.15e-40: 149: 35.39
+	Hs
		382485 HLAA_HUMAN (1-365): 1.04e-179: 504: 81.92		LIRB1_HUMAN (21-258): 8.15e-40: 149: 35.39
+	Hs
		1130838 Q5S3G3_HUMAN (1-365): 1.02e-178: 501: 82.19		LIRB1_HUMAN (21-258): 8.15e-40: 149: 35.39
+	Hs
		1232786 Q95J06_HUMAN (1-365): 0: 514: 80.55		LIRB2_HUMAN (10-138): 5.67e-15: 77.1: 35.66
+	Hs
		382478 HLAA_HUMAN (1-365): 1.04e-179: 504: 81.92		LIRB2_HUMAN (10-138): 5.67e-15: 77.1: 35.66
+	Hs
		1130837 Q5S3G3_HUMAN (1-365): 1.02e-178: 501: 82.19		LIRB2_HUMAN (10-138): 5.67e-15: 77.1: 35.66