HitPredict

Interactor 1: H2AZ (P0C0S5)
Histone H2A.Z (H2A/z)
Gene: H2AZ1

Interactor 2: UBB (P0CG47)
Polyubiquitin-B [Cleaved into: Ubiquitin]
Gene: UBB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	28242625, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 128 Hs			1 229
+	Hs
		474911 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		UBB_HUMAN (1-229): 4.07e-98: 286: 100.00
+	Dm
		446330 H2AV_DROME (1-125): 2.57e-60: 183: 96.00		R9PY16_DROME (1-220): 3.01e-86: 259: 91.82
+	Rn
		470237 H2AZ_RAT (1-128): 9.79e-62: 186: 100.00		UBC_RAT (1-181): 2.6e-61: 206: 96.13
+	Rn
		474085 H2A2A_RAT (5-125): 4.61e-55: 169: 62.30		UBC_RAT (1-181): 2.6e-61: 206: 96.13
+	Hs
		469930 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		UBC_HUMAN (1-153): 4.05e-53: 183: 99.35
+	Hs
		476233 H2A1A_HUMAN (5-125): 2.16e-56: 173: 61.48		UBC_HUMAN (1-153): 4.05e-53: 183: 99.35
+	Hs
		476271 H2A1J_HUMAN (5-125): 1.24e-55: 171: 61.48		UBC_HUMAN (1-153): 4.05e-53: 183: 99.35
+	Hs
		475833 H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29		UBC_HUMAN (1-153): 4.05e-53: 183: 99.35
+	Hs
		391519 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		UBC_HUMAN (1-153): 4.05e-53: 183: 99.35
+	Hs
		475312 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		UBC_HUMAN (1-153): 4.05e-53: 183: 99.35
+	Hs
		475912 H2A2A_HUMAN (5-125): 4.61e-55: 169: 62.30		UBC_HUMAN (1-153): 4.05e-53: 183: 99.35
+	Hs
		924047 H2AV_HUMAN (1-127): 2.06e-60: 183: 98.43		RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00
+	Hs
		391643 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00
+	Hs
		470331 H2A1_HUMAN (5-125): 8.23e-55: 169: 61.48		RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00
+	Hs
		555403 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00
+	Hs
		924034 H2A2A_HUMAN (5-125): 4.61e-55: 169: 62.30		RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00
+	Hs
		924049 H2A3_HUMAN (5-125): 5.08e-55: 169: 62.30		RS27A_HUMAN (153-228): 1.76e-44: 147: 100.00
+	Hs
		470393 H2A1_HUMAN (5-125): 8.23e-55: 169: 61.48		OASL_HUMAN (1-153): 3.31e-21: 93.2: 29.11